麻豆高清

靸濎泊鞛�耄� 攵勳暭 靹戈硠鞝� 甓岇渼 頃欖垹歆� Bioactive Martials鞐� 瓴岇灛

霃欔淡雽� 鞚橃儩氇呹车頃欔臣 欷勱赴靹疙彫瓿淀暀 鞐瓣惮鞁�(鞚挫垬頇� 甑愳垬 鞐瓣惮韺�)鞐愳劀 鞝� 1鞝�鞛愲�� 旯�雿曥澕 氚曥偓鞕� 鞚措�检＜ 氚曥偓瓿检爼 頃欖儩鞚� 歆勴枆頃� “靹疙彫 鞐�攵勴檾 頄レ儊鞚� 鞙勴暅 頌堨晫耄�搿犾偘 頃橃澊霌滊�滌牑瓿� 鞝�臧曤弰 齑堨潓韺� 鞛愱饭 鞙淀暕 鞁滌姢韰� (Ultrasound-triggered three-dimensional hyaluronic acid hydrogel promotes in vitro and in vivo reprogramming into induced pluripotent stem cells)” 鞐瓣惮臧� 斓滉芳 靸濎泊鞛�耄� 攵勳暭鞚� 甓岇渼鞛堧姅 頃欖垹歆� Bioactive Materials, 38, 331-345 (IF=18.9, JCR 霝�韨� 靸侅渼 1.1%)鞐� 瓴岇灛霅愲嫟. 

鞙犽弰毵岆姤 欷勱赴靹疙彫電� 氅挫棴瓯半秬氚橃潙鞚� 臧�電レ劚鞚� 雮�瓿� 氚办晞欷勱赴靹疙彫鞕� 甏�霠�霅� 鞙るΜ鞝� 氍胳牅毳� 頃搓舶頃橂┐靹� 毵岆姤靹膘潣 韸轨劚鞚� 歆�雼堦赴 霑岆�胳棎 靹疙彫 旃橂��, 歆堧硲 鞀ろ伂毽�雼�, 鞁犾暯臧滊皽 霌� 雼れ枒頃� 鞛�靸濎潣頃� 攵勳暭鞐� 頇滌毄霅橁碃 鞛堧嫟. 

霕愴暅 頇橃瀽鞚� 觳挫劯韽�搿滊秬韯� 鞙犽弰頃� 鞙犽弰毵岆姤 欷勱赴靹疙彫電� 頇橃瀽 臧滌澑鞚� 鞙犾爠鞝� 韸轨劚瓿� 靹疙彫鞝� 韸轨劚鞚� 瓿犽牑頃� 臧滌澑 毵烄钉順� 旃橂�岅皜 臧�電ロ晿雼�. 頃橃��毵� 鞙犽弰毵岆姤 欷勱赴靹疙彫毳� 鞙犽弰頃橂姅 旮办〈 氚╇矔霌れ潃 雮�鞚� 須�鞙�靹� (1-5%)鞚� 氍胳牅鞝愳潉 臧�歆�旮� 霑岆�胳棎 鞐�攵勴檾 須�鞙� 歃濎�� 旮办垹臧滊皽鞚� 毵れ毎 欷戩殧頃� 鞐瓣惮 攵勳暭雼�. 

鞚措矆 鞐瓣惮鞐愳劀電� 3彀�鞗� 頇橁步鞚� 頌堨晫耄�搿犾偘(HA) 頃橃澊霌滊�滌牑鞐愳劀鞚� 鞝�臧曤弰 齑堨潓韺� 鞛愱饭鞚� 鞙犽弰毵岆姤 欷勱赴靹疙彫搿滌潣 鞐�攵勴檾 須�鞙�鞚� 旮办〈 氚╇矔雽�牍� 15氚� 鞚挫儊 歃濌皜鞁滍偆電� 瓴冹潉 頇曥澑頄堧嫟. 霕愴暅, 鞝�臧曤弰 齑堨潓韺� 鞛愱饭鞚� 靹疙彫瓿�瓴� 甑�臁办潣 氤�頇旊ゼ 臁办爤頃� 靹疙彫毵夓潣 鞙犽彊靹膘潉 歃濌皜鞁滍偆瓿� 靹疙彫毵� 靾橃毄觳挫檧 毽�臧勲摐鞚� 瓴绊暕鞚� 頄レ儊鞁滍偓 靾� 鞛堦碃, 鞚措煬頃� 氤�頇旊姅 HA/CD44 瓴绊暕鞚� 齑夓�勴晿鞐� CD44鞚� 頃橃渼 鞁犿樃鞝勲嫭 瓴诫�滌澑 STAT3 氚� AKT鞚� 頇滌劚頇旊ゼ 鞙犽弰頃橁矊 霅橃柎 甓侁饭鞝侅溂搿� 鞐�攵勴檾臧� 歃濎�勲悩電� 鞐�攵勴檾 氅旍护雼堨�橃潉 鞝滌嫓頄堧嫟. 

鞚挫垬頇� 甑愳垬電� "鞙犽弰毵岆姤 欷勱赴靹疙彫電� 鞛�靸濎潣頃� 攵勳暭鞐� 毵れ毎 欷戩殧頃� 鞛愳洂鞚措┌, 鞚� 旮办垹鞚� 韱淀暣 旮办〈 氚╇矔霌れ潣 雮�鞚� 須�鞙�靹膘潣 氍胳牅 頃搓舶鞚� 臧�電ロ晿瓴� 頃橃棳 鞙犽弰毵岆姤 欷勱赴靹疙彫鞚� 雽�霟夓儩靷办潉 順勳嫟頇旐晿氅� 臧滌澑 毵烄钉順� 鞚橅暀 氚滌爠鞐� 旮办棳頃� 瓴冹溂搿� 旮半寑霅滊嫟"瓿� 氚濏様雼�. 頃滍幐, 鞚措矆 鞐瓣惮 瓴瓣臣電� 頃滉淡鞐瓣惮鞛�雼� 欷戧铂鞐瓣惮歆�鞗愳偓鞐�, 氚旍澊鞓れ潣耄岅赴靾犼皽氚滌偓鞐�, 靹胳�呹臣頃� 韼犽�滌毎鞁� 靷�鞐� 霌膘潣 歆�鞗愳潉 韱淀暣 鞚措�勳�岆嫟.